The world is no stranger to losses, but none as prolific as Oprah. Oprah gained fame with her talkshow that started in the 1980's and is still running today .
The world is also no stranger to Hollywood losses. Again, none as prolific as Oprah. She started out weighing just over two hundred pounds and shocked the world when she lost sixty-seven pounds. She then climbed back up the weight ladder and started a yo-yo effect with weight .